The rare and inexplicable Puberty Syndrome is thought of as a myth. It is a rare disease which only affects teenagers, and its symptoms are so supernatural that hardly anyone recognizes it as a legitimate occurrence. However, high school student Sakuta Azusagawa knows from personal experience that it is very much real, and happens to be quite prevalent in his school.
Mai Sakurajima is a third-year high school student who gained fame in her youth as a child actress, but recently halted her promising career for reasons unknown to the public. With an air of unapproachability, she is well known throughout the school, but none dare interact with her—that is until Sakuta sees her wandering the library in a bunny girl costume. Despite the getup, no one seems to notice her, and after confronting her, he realizes that she is another victim of Puberty Syndrome. As Sakuta tries to help Mai through her predicament, his actions bring him into contact with more girls afflicted with the elusive disease.
[Written by MAL Rewrite]+ More
Characters & Voice Actors

Azusagawa, Sakuta
Main
Sakurajima, Mai
Main
Azusagawa, Kaede
Supporting
Futaba, Rio
Supporting
Hanawa, Ryouko
Supporting
Hirokawa, Uzuki
Supporting
Kamisato, Saki
Supporting
Kano, Kotomi
Supporting
Kashiba, Rena
Supporting
Koga, Tomoe
SupportingRecommended for you
Endless Orbit SSX
TV
25m
Yozakura Quartet: Hoshi no Umi
OVA
28m
Nisekoi: False Love
TV
24m
Re: Hamatora: Season 2
TV
24m
Tanaka-kun is Always Listless
Special
4m
Un-Go
TV
24m
One Piece: Romance Dawn Story
OVA
33m
One Punch Man 2nd Season
TV
23m
Tokyo Ghoul: "Jack"
OVA
30m
Urusei Yatsura OVA
OVA
32m
Wei, Kanjian Erduo La! 2
ONA
3m
Aikatsu! Movie
Movie
88m
Someone's Gaze
Movie
6m